Answer : A
Explanation : Working in rows, if you superimpose the pattern of spots in the left and right hand grids you get the pattern in the central grid.
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Answer : O
Explanation : Working in rows, add up the digits in each row and put the letter with this numerical value in the centre of the row.
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Answer : 5
Explanation : In each row, add together the numerical values of the 3 central letters to give a 2 digit sum, and put this 2 digit sum in the left and right hand boxes at the end of the rows.